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Scientists successfully create age-resistant mice with hyper-long telomeres
Black [email protected]
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11-07-2019 12:33 AM

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Post: #1
devil Scientists successfully create age-resistant mice with hyper-long telomeres
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Researchers at the Spanish National Cancer Research Centre (CNIO) have shown that it is possible to extend the life of mice, without using any gene modifying technologies. The finding is the result of a study launched some years ago that aimed to investigate mice with hyper-long telomeres.

Chromosome

Image Credit: Crevis / Shutterstock.com

Given the relationship between telomeres and aging (telomeres become shorter with age), Maria Blasco and colleagues decided to create mice at CNIO that had hyper-long telomeres in 100% of their cells.

The researchers reported their findings in the journal Nature Communications and demonstrate only positive outcomes; the mice live for longer and in better health than would be expected for their species, while also being free from age-related conditions such as cancer and obesity.
No need for genetic modification

The most important finding for the team was that the increased lifespan and health benefits have been achieved for the first time without genetic modification being needed.

"This finding supports the idea that, when it comes to determining longevity, genes are not the only thing to consider", says Blasco… "There is margin for extending life without altering the genes.”

Telomeres form the end of chromosomes in the nucleus of cells and protect the genetic integrity of DNA. Each time a cell divides, the telomeres shorten a little, so one characteristic of aging is shortened telomeres in cells.

https://www.news-medical.net/news/201910...RnsqGcbwak

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seasnake
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11-07-2019 12:36 AM

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Post: #2
RE: Scientists successfully create age-resistant mice with hyper-long telomeres
that is fantastic, long-life slow-aging mice is just what the planet needs
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Black [email protected]
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11-07-2019 12:39 AM

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Post: #3
RE: Scientists successfully create age-resistant mice with hyper-long telomeres
seasnake  Wrote: (11-07-2019 12:36 AM)
that is fantastic, long-life slow-aging mice is just what the planet needs

Well if it can be done to mice and they talking about it
Don't think they doing it humans already ?

Sometimes you gotta play the role of the fool,
To fool the fool who thinks they're fooling you

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seasnake
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11-07-2019 12:46 AM

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Post: #4
RE: Scientists successfully create age-resistant mice with hyper-long telomeres
Black [email protected]  Wrote: (11-07-2019 12:39 AM)
seasnake  Wrote: (11-07-2019 12:36 AM)
that is fantastic, long-life slow-aging mice is just what the planet needs

Well if it can be done to mice and they talking about it
Don't think they doing it humans already ?

many experiments that work with mice do not transfer over to working on people

Drugs That Work In Mice Often Fail When Tried In People - NPR
https://www.npr.org/sections/health-shot...-in-people
Apr 10, 2017 - Most potential new drugs don't work when tested in people. ... Garner says scientists shouldn't even be trying to do experiments this way.
(This post was last modified: 11-07-2019 12:46 AM by seasnake.) Quote this message in a reply
Black [email protected]
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11-07-2019 12:47 AM

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Post: #5
RE: Scientists successfully create age-resistant mice with hyper-long telomeres
seasnake  Wrote: (11-07-2019 12:46 AM)
Black [email protected]  Wrote: (11-07-2019 12:39 AM)
Well if it can be done to mice and they talking about it
Don't think they doing it humans already ?

many experiments that work with mice do not transfer over to working on people

Drugs That Work In Mice Often Fail When Tried In People - NPR
https://www.npr.org/sections/health-shot...-in-people
Apr 10, 2017 - Most potential new drugs don't work when tested in people. ... Garner says scientists shouldn't even be trying to do experiments this way.

I am not saying the same drugs, I am saying the concept of making the telomeres longer equals longer age

Sometimes you gotta play the role of the fool,
To fool the fool who thinks they're fooling you

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(This post was last modified: 11-07-2019 12:48 AM by Black [email protected].) Quote this message in a reply
Uppity Me
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11-07-2019 12:51 AM

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Post: #6
RE: Scientists successfully create age-resistant mice with hyper-long telomeres
so just inject or take Telomerase every day
no more need for babies blood

Quote:Les pauvres n'ont-ils des Euros ?
Alors laissez les pauvres 'sh*t' dans les rues
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seasnake
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11-07-2019 12:53 AM

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Post: #7
RE: Scientists successfully create age-resistant mice with hyper-long telomeres
Black [email protected]  Wrote: (11-07-2019 12:47 AM)
seasnake  Wrote: (11-07-2019 12:46 AM)
many experiments that work with mice do not transfer over to working on people

Drugs That Work In Mice Often Fail When Tried In People - NPR
https://www.npr.org/sections/health-shot...-in-people
Apr 10, 2017 - Most potential new drugs don't work when tested in people. ... Garner says scientists shouldn't even be trying to do experiments this way.

I am not saying the same drugs, I am saying the concept of making the telomeres longer equals longer age

That has always been thought of telomeres. It used to be believed that telomeres only became smaller as a person ages all the way from their birth to their death. That notion that they could not grow back longer was however proven wrong. I haven't looked it up for awhile, so I don't know exactly what they are currently claiming or saying about them at the moment.
(This post was last modified: 11-07-2019 12:53 AM by seasnake.) Quote this message in a reply
Black [email protected]
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11-07-2019 12:54 AM

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Post: #8
RE: Scientists successfully create age-resistant mice with hyper-long telomeres
seasnake  Wrote: (11-07-2019 12:53 AM)
Black [email protected]  Wrote: (11-07-2019 12:47 AM)
I am not saying the same drugs, I am saying the concept of making the telomeres longer equals longer age

That has always been thought of telomeres. It used to be believed that telomeres only became smaller as a person ages all the way from their birth to their death. That notion that they could not grow back longer was however proven wrong. I haven't looked it up for awhile, so I don't know exactly what they are currently claiming or saying about them at the moment.

With Crisper and the likes, I wonder how long till someone does some stretching chuckle

Sometimes you gotta play the role of the fool,
To fool the fool who thinks they're fooling you

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I'm Just A Dancing Clown Dancing All Around
(This post was last modified: 11-07-2019 12:54 AM by Black [email protected].) Quote this message in a reply
seasnake
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11-07-2019 12:54 AM

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Post: #9
RE: Scientists successfully create age-resistant mice with hyper-long telomeres
Uppity Me  Wrote: (11-07-2019 12:51 AM)
so just inject or take Telomerase every day
no more need for babies blood

don't be silly, you need babies blood to appease the gods, same always
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seasnake
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11-07-2019 12:57 AM

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Post: #10
RE: Scientists successfully create age-resistant mice with hyper-long telomeres
Black [email protected]  Wrote: (11-07-2019 12:54 AM)
seasnake  Wrote: (11-07-2019 12:53 AM)
That has always been thought of telomeres. It used to be believed that telomeres only became smaller as a person ages all the way from their birth to their death. That notion that they could not grow back longer was however proven wrong. I haven't looked it up for awhile, so I don't know exactly what they are currently claiming or saying about them at the moment.

With Crisper and the likes, I wonder how long till someone does some stretching chuckle

the biggest hurdle if one could live pretty much forever is that they eyes don't last that long and people would go blind fairly early as well as deaf... eye tech that is coming out is supposed to resolve that though
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Shoggoth
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11-07-2019 01:02 AM

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Post: #11
RE: Scientists successfully create age-resistant mice with hyper-long telomeres
This is cool. Probably won't go into effect for humans before my time is up. But if it did I wouldn't mind living to 1,000 or so.
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⚡Falcon⚡
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11-07-2019 01:03 AM

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Post: #12
RE: Scientists successfully create age-resistant mice with hyper-long telomeres
seasnake  Wrote: (11-07-2019 12:36 AM)
that is fantastic, long-life slow-aging mice is just what the planet needs

Haha.

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seasnake
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11-07-2019 01:14 AM

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Post: #13
RE: Scientists successfully create age-resistant mice with hyper-long telomeres
Shoggoth  Wrote: (11-07-2019 01:02 AM)
This is cool. Probably won't go into effect for humans before my time is up. But if it did I wouldn't mind living to 1,000 or so.

I'm sure if it ever goes into effect for humans, that is long life extension/immortality type stuff that there will be a human culling first to reduce the population down to something more controllable and sustainable. Long life extension won't be for everyone.



(This post was last modified: 11-07-2019 01:15 AM by seasnake.) Quote this message in a reply
Wild Stallion
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11-07-2019 01:15 AM

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Post: #14
RE: Scientists successfully create age-resistant mice with hyper-long telomeres
seasnake  Wrote: (11-07-2019 12:36 AM)
that is fantastic, long-life slow-aging mice is just what the planet needs

Yeah, forget about inventing a new mouse trap, what we really need is a new mouse.

Lmonkey
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seasnake
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11-07-2019 01:17 AM

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Post: #15
RE: Scientists successfully create age-resistant mice with hyper-long telomeres
Wild Stallion  Wrote: (11-07-2019 01:15 AM)
seasnake  Wrote: (11-07-2019 12:36 AM)
that is fantastic, long-life slow-aging mice is just what the planet needs

Yeah, forget about inventing a new mouse trap, what we really need is a new mouse.

when growing the population is no longer necessary or required, the next question becomes just how much of a population is actually desired and needed

I guess that is what the Georgia Guidestones are for.
(This post was last modified: 11-07-2019 01:19 AM by seasnake.) Quote this message in a reply
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